Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #wtNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#wtNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS |
| Enrichment Score (ES) | -0.7359057 |
| Normalized Enrichment Score (NES) | -1.823484 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03174179 |
| FWER p-Value | 0.024 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CSNK1G3 | 110450 | 2021 | 0.525 | -0.0864 | No | ||
| 2 | SIN3B | 6650253 | 2214 | 0.468 | -0.0767 | No | ||
| 3 | SUFU | 6650181 | 2396 | 0.413 | -0.0688 | No | ||
| 4 | SAP18 | 3610092 | 4231 | 0.141 | -0.1615 | No | ||
| 5 | RBBP7 | 430113 450450 2370309 | 4730 | 0.110 | -0.1836 | No | ||
| 6 | CSNK1G1 | 840082 1230575 3940647 | 5224 | 0.086 | -0.2065 | No | ||
| 7 | FOXA2 | 540338 5860441 | 5301 | 0.082 | -0.2070 | No | ||
| 8 | GNAI3 | 4670739 | 5446 | 0.077 | -0.2115 | No | ||
| 9 | MTSS1 | 780435 2370114 | 6342 | 0.049 | -0.2576 | No | ||
| 10 | GLI3 | 5690148 | 6365 | 0.048 | -0.2567 | No | ||
| 11 | PTCH1 | 430278 | 6861 | 0.038 | -0.2817 | No | ||
| 12 | FBXW11 | 6450632 | 7959 | 0.018 | -0.3400 | No | ||
| 13 | GLI1 | 4560176 | 8553 | 0.010 | -0.3715 | No | ||
| 14 | AKT1 | 5290746 | 9115 | 0.002 | -0.4016 | No | ||
| 15 | XPO1 | 540707 | 9544 | -0.004 | -0.4245 | No | ||
| 16 | MAP2K1 | 840739 | 9684 | -0.006 | -0.4317 | No | ||
| 17 | GNAI1 | 4560390 | 11052 | -0.026 | -0.5042 | No | ||
| 18 | SHH | 5570400 | 11968 | -0.043 | -0.5516 | No | ||
| 19 | PRKCD | 770592 | 13430 | -0.086 | -0.6266 | No | ||
| 20 | GNAO1 | 2510292 6590487 | 13432 | -0.086 | -0.6230 | No | ||
| 21 | GNAZ | 6130296 | 13586 | -0.092 | -0.6273 | No | ||
| 22 | CSNK1A1 | 2340427 | 14110 | -0.119 | -0.6504 | No | ||
| 23 | PRKACA | 2640731 4050048 | 14523 | -0.149 | -0.6662 | No | ||
| 24 | GLI2 | 3060632 | 14583 | -0.155 | -0.6627 | No | ||
| 25 | SMO | 5340538 6350132 | 14812 | -0.175 | -0.6675 | No | ||
| 26 | RAB23 | 2970075 | 15034 | -0.202 | -0.6708 | No | ||
| 27 | ARRB2 | 2060441 | 16245 | -0.443 | -0.7170 | Yes | ||
| 28 | PIAS1 | 5340301 | 16304 | -0.467 | -0.7001 | Yes | ||
| 29 | RBBP4 | 6650528 | 16496 | -0.524 | -0.6880 | Yes | ||
| 30 | HDAC1 | 2850670 | 16596 | -0.560 | -0.6693 | Yes | ||
| 31 | CREBBP | 5690035 7040050 | 17223 | -0.828 | -0.6676 | Yes | ||
| 32 | KIF3A | 5050348 6650079 | 17270 | -0.850 | -0.6337 | Yes | ||
| 33 | HDAC2 | 4050433 | 17296 | -0.861 | -0.5982 | Yes | ||
| 34 | SAP30 | 5080735 | 17544 | -0.997 | -0.5688 | Yes | ||
| 35 | GSK3B | 5360348 | 17561 | -1.000 | -0.5268 | Yes | ||
| 36 | CSNK1G2 | 3060095 4730037 | 17583 | -1.004 | -0.4850 | Yes | ||
| 37 | SPOP | 450035 | 17747 | -1.104 | -0.4465 | Yes | ||
| 38 | CSNK1E | 2850347 5050093 6110301 | 17859 | -1.190 | -0.4015 | Yes | ||
| 39 | SIN3A | 2190121 | 17952 | -1.256 | -0.3527 | Yes | ||
| 40 | GNB1 | 2120397 | 18190 | -1.508 | -0.3009 | Yes | ||
| 41 | GNG2 | 2230390 | 18284 | -1.627 | -0.2363 | Yes | ||
| 42 | CSNK1D | 4280280 4480167 6450600 | 18374 | -1.818 | -0.1633 | Yes | ||
| 43 | IFT172 | 3800372 7100400 | 18391 | -1.876 | -0.0839 | Yes | ||
| 44 | LGALS3 | 2120239 | 18512 | -2.241 | 0.0056 | Yes |
